An acquired absence of pigment found in spots or patches, although the margin of these spots shows an increased amount of pigment matter. (J. Henery Allen)

 Oral psoralen therapy
Oral psoralen therapy is known as domestic remedy for the treatment of vitiligo, mostly formulated for people with more extensive vitiligo, (greater then 20%). It is applied through psoralea corylifolia seeds. Oral psoralen therapy is not recommended for children as it causes many skin problems including skin cancer, also increase the risk of eyes damages. The treatment is more effective to get recovery or cure from vitiligo by the combination of sun rays or sun exposure.

For oral psoralen therapy, the doctor recommends patient to take a prescribed dose of psoralen drug before the treatment. On a domestic shell, it is advised avoid to take psoralen (a seed of psoralea corylifolia), by self, because it is very potent substance and should not be used without the counsel of doctor. The basic purpose of psoralen drug is to enhance the skin sensitivity of a person.

PUVA Treatment
Photochemotherapy or PUVA is an acronym where "P" stands for "Psoralen" and "UVA" stands for long wavelength UV light. It is a type of ultraviolet radiation treatment, used for severe skin diseases. Psoralen is a compound, mostly found in plants that help to increase the skin sensitivity to face UVA. Before the treatment, psoralen drug is given to patient. Different medicines include psoralen such as methoxsalen (8-methoxypsoralen), 5-methoxypsoralen and trisoralen.

Topical psoralen therapy
Substitute of (orally) psoralen; psoralen substance is taken in the variety of topical applications. Topical applications includes different creams & lotions etc, those are applied to certain areas of skin, but affective only to those areas which it is applied.

Anti vitiligo oil is very popular as it takes psoralea corylifolia ingredient, to treat vitiligo skin condition. It is an herbal product, producing from natural herbs, free from chemicals, with no side effects, and suitable for every type (including sensitive) skin.

Ayurvedic Treatment
Vitiligo appears in many people due to the insufficiency of nutritional factors like magnesium, potassium, calcium, protein, iron, calcium, vitamins, phosphorous etc. The Ayurvedic treatment gives much consequence to obtain balanced diet along with vitiligo medicines.  A local application ‘Babchi oil’ is recommended from many physicians. Physicians in this treatment recommend to patient to take multivitamin, or calcium tablets or injections.

UVB and Psoralen Treatment:
 In Photochemotherapy or light therapy Psoralen drug along with UVB shorter wave length (315-280nm) is used, in order to re-produce pigmentary cells in skin. UVB rays have more power or energy in re-producing pigmentary cells in skin & more side effects. Children should be avoided from this kind of treatment as it can damages the vision of eyes, and also cause of skin cancer.

Homeopathic Treatment
Homeopathic treatment is most well-liked treatment considered now days, because of treating vitiligo skin conditions by natural products, which are produced from natural sources, free from chemicals, suitable for every skin with no side effects.

Anti Vitiligo oil is very popular to treat vitiligo skin conditions due to the herbal ingredients like Coconut oil, Psoralea corylifolia (Babchi oil), Black Cumin etc.

Topical Applications
Topical applications are includes creams, sun-creams, lotions. Many vitiligo topical applications are available in market that can help a patient to treat vitiligo skin affected areas.

Topical Oxsoralen or Spot Treatment
Oxsoralen is highly phototoxic. So it should be used if physician recommends, and it is only applicable on small vitiligo spots.

Autologous skin grafts
In this treatment physician takes pigment producing cells from any part of body with the help of surgical tools, transfer it to those parts of body, which have no or less pigment cells, also known as transplantation.